Swelling after removal of the thyroid gland

Thyroid. not having excretory ducts - refers to a series of glands

with the internal secretion ie, whose chemical products are necessary

to maintain a healthy state of the body, are not derived from them

by any excretory ducts, but come from them directly into the

blood and lymph and are carried by them throughout the body. Thyroid function of the beginning

to clear up since the surgeons Reverden (1882) and Kocher (1883).

noticed that after complete removal of the thyroid gland, as was done

before, for example. at a struma (a hypertrophy of a thyroid gland) or at malignant

her tumors, etc., a series of painful seizures, ending

usually death. After complete removal of the thyroid gland are observed through

for some time, abrupt changes in both physical and mental

body condition; due to a violation of the correct metabolism, and

track. and the total nutrition of the body, a special puffiness develops,

swelling of the whole body, especially the face, facial features

disfigure, mucosal degeneration of tissues develops - mix "deme,

Muscular weakness more and more progressing, various nervous

disorders with simultaneous development of mental stupidity, very

reminiscent of the state of cretinism. All this picture of disorders is given

name of Strumipriva cachexia. On the other hand, experimental

The study of the physiologist Schiff in 1859 and in 1884. Albertoni, Tizzoni,

Rogovich, Glei and others on dogs, cats and monkeys showed that the full

the removal of the thyroid gland entails the death of animals,

the latter die after several weeks from various kinds of nervous

disorders. The data from the pilot studies coincide in this way with

surveillance of surgeons and the thyroid gland should be attributed to a tremendous value

in the maintenance of normal metabolism and, in particular, in

central nervous system. The nature of this influence seems,

However, it is still far from being clarified and exists so far on this account only

a number of more or less probable hypotheses. Schiff of the opinion that the thyroid gland

produces some substance that is extremely important for proper nutrition, in

Features of the brain and in particular of its nerve centers and

delivers this substance through internal secretion. that is, directly into the bloodstream and

lymph and in favor of it speak, apparently. the following facts having

of enormous practical importance. Inoculation of the thyroid gland in the abdominal cavity

Dogs without this gland, as Gley did, completely protects

dogs from all the painful consequences of bilateral full

thyroidectomy (i.e., cutting out the thyroid gland) and the dog, without it

inevitably doomed to death, perfectly survive. Even injection

thyroid gland relief facilitated severe seizures of such thyroidectomized

dogs and slowed down the onset of the fateful denouement. These are the facts and lay down in

the basis of the currently practiced treatment of the mix "demos in humans injections

extracts from the thyroid gland, treatment, which still gives the most beneficial

results. The above experimental data allow, however,

another kind of explanation; namely, that the importance of the thyroid gland is not that,

to produce some substance necessary for nutrition

central nervous system, and neutralize, destroy and thereby

remove from the animal economy some harmful, unknown products

life exchange, some toxins that accumulate in their blood

all the body and especially the central nervous system are poisoned, and this

opinions are held by Rogovic (1886). And in favor of this is the following

data. Blood taken from dogs with a distant thyroid gland in the developed

all painful symptoms, being injected into the animal with a recent

produced by thyroidectomy, accelerates the onset of all

painful phenomena, whereas the same blood, when introduced to normal

An animal does not cause any harmful effects on it.

the fact that the thyroid gland of normal animals neutralizes harmful principles -

toxins of blood taken from sick animals (Rogovic and Gley). Fano, except

Moreover, he proved that the disorders that have already occurred on the animal with the removed

thyroid gland, can be weakened or even completely eliminated if done

his bloodletting and replace his harmful blood with the blood of a normal

animal. Finally, it is noted (Lolanje and Mazuen) that the urine of animals with

removed by the thyroid gland becomes more and more poisonous in nature,

the development of painful seizures. These last facts speak in

benefit of the fact that animals with a distant thyroid gland are the victims of

then the toxins accumulating in the body in the absence of the thyroid gland. Finally

Notkin managed to extract from the thyroid gland an albuminoid, named by him

thyreoprotein, which, when injected into a normal animal, causes

they have a picture of painful seizures characteristic of animals with a remote

With the gland, i.e. Strumipriva cachexia. But his opinion, the substance is and

there is that toxin that develops in the body of animals with a removed SCH.

gland and neutralized by it under normal conditions. It's great that

beneficial effect of the infusions of the thyroid gland on animals with removed SCH.

The gland affects not only when they are administered under the skin or into the veins, but also

when they are introduced into the digestive canal, and this extract can

be either in the form of powder, tablets, etc. It is obvious that the current

the beginning of the thyroid gland is very resistant, does not collapse under the

influence of digestive juices and, as experiments have shown, even under the influence of

boiling point. Based on all the facts presented here, N.

Vvedensky acknowledges already established that in the blood of animals with a remote

Thyroid gland indeed accumulates some poisonous products and that

The painful phenomena in them go in parallel with the development and accumulation

these products. Naturally, after all this, the desire of various

researchers to isolate from the thyroid gland an active substance that neutralizes

toxin of this cachexia Strumiprivi and playing, therefore, the role of

antitoxin or antidote. But only Bauman and Roos managed to extract

from the thyroid gland the desired substance, apparently, a substance called iodothyrine

or thyroidin; it contains 9.3% iodine in a strong bond with the organic

nucleus and in the very iron gland this substance is in association with albumin and

partly with the globulin and only a small part of it is

free. The significance of iodotirin is advanced by the remarkable fact that

it is a substance when it is introduced into the organism of animals with the removed SCH.

The gland acts on them as beneficially as the fresh gland itself

or cooked from her medicinal preparations. On dogs with uch.

gland, while given daily 2 gr. iodothyrine, did not develop at all

seizures; it was necessary to stop for a few days the intake of this substance, as

again there were cramps, etc. It would be very interesting to know

how active in this respect are corrupt

preparations of thyroidin, which should not be mixed with iodothyrine

Bauman. Very interesting is the following discovery of Bauman: according to his

analyzes, the only organ of the animal body that contains iodine,

is the thyroid gland and the content of iodine in it is variable according to the species

animals and various food conditions and even inhabited people

terrain. In areas with a very common goiter and cretinism, in

thyroid gland contains little iodine and vice versa in areas free from

of this disease, in the iron gland people find from 3

- 4 milligrams. iodine. Obviously, this dependence is determined by

more or less iodine content in the soil, and through it both in the waters and

plant foods in one or another area. Small

the content of iodine or its absence in soil is one of the conditions.

contributing to the development of goiter and cretinism. Iodine content in the thyroid gland

fluctuates also with the age of people: in childhood and adolescence -

iodine is less, in adults more, and in senile again decreases and iron

is reborn. Thus, one of the main functions of the thyroid gland serves,

apparently, its ability to accumulate in itself iodine and form a complex

substance - iodothyrine, and maybe also other iodine-containing

compounds that are destined to play a significant role of antivenom against

accumulating, with a vital metabolism, toxins. Iodine,

therefore, is necessary for the life of the higher organized beings and

should therefore be included in the number of biogenic elements. Healing

the action of the thyroid gland is one of the most brilliant proofs

the reality of organ therapy being built up and growing day by day.