Edema of the walls of the stomach

The purpose of the topic and questions to it

Is the goal set? to study the pathogenesis of the development of colienterotoxemia, pathoanatomical changes and diagnosis of the disease.

Colienterotoxemia (edematous disease) ?? sick pigs after their weaning, is characterized ?? nerve problems, diarrhea, edema of organs and tissues, more often the walls of the stomach, mesentery of large intestines and subcutaneous tissue in the region of the head and abdomen.

Etiology and pathogenesis. Exciters of Escherichia coli.

In the pathogenesis of the disease, unfavorableconditions, a change in the mode of feeding, which cause digestive disorders, the prevalence of toxigenic strains of Escherichia coli in the intestine. With the weakening of general resistance, the causative agent multiplies extensively and releases endo? and exotoxins. Toxins are adsorbed by villi of epithelial cells of small intestines, causing increased secretion and excretion of water and electrolytes from the body, the development of acidosis. Penetrating into the blood and lymph, the causative agent causes septicemia. Intoxication contributes to the development of acute heart failure, vascular disorders, there are swelling in different parts of the body.

  1. Insufficient feeding of piglets during the period of intensive growth and development (2 ן months).
  2. Sharply weaning the piglets from the sow.
  3. Depriving mother-milk and transfer toconcentrate diet, which leads to digestive disorders (dyspepsia), dystrophy and necrobiosis of the intestinal mucosa and the formation of toxic products of their decay. Against this background, dysbacteriosis develops with a predominance of toxic beta-hemolytic strains of Escherichia coli.

The metabolic products of bacteria contribute to an increase in the permeability of blood vessels, which leads to the penetration of toxins into the blood, an increase in the general intoxication of the organism and the suppression of immunity.

Piglets get sick at 7? 12th day after weaning.

The current can be a super-fast duration of 5 ??18h, sharp ?? 2 ?? 3 days, the super-sharp and acute current is noted with early weaning piglets in 4 ?? 6 ?? Weekly age, subacute ?? 5?? 8 days. subacute ?? at a later time ?? 10?? 12 ?? week.

Pathoanatomical picture depends on the severity of the course of the disease. Over-flowing current has no characteristic changes. Focal cyanosis of the skin, minor eyelid edema, catarrhal gastroenteritis, swelling and hyperemia of mesenteric lymph nodes.

In acute course changes are more pronounced. This is swelling in different organs and tissues. This is the edema of the eyelids, conjunctiva, in the subcutaneous tissue of the nose, forehead, the base of the auricles, the trachea, the abdomen. The nature of edematous tissue is gelatinous. From internal organs, there is edema of the stomach wall (cardial part), mesentery and the wall of the large intestine. In the stomach, they find food of a firm consistency or thick masses. Expressed folding and hyperemia of the mucosa, covering it with mucus, the wall of the stomach thickened. In the thin section ?? congestive hyperemia and acute catarrhal enteritis.

  1. Unsure congestive congestion of the auricles and ventral abdominal wall, sometimes ?? slight swelling and weak swelling of the eyelids.
  2. The mucous membrane of the stomach in the bottom area is reddened, the wall is sometimes slightly thickened, edematous.

Reaction of mesenteric lymph nodesis noted in the form of their puffiness, juiciness on a cut and mosaic pattern. The spleen usually has no visible changes. In the parenchymal organs, dystrophic changes and circulatory disorders. Characterized by swelling of the lungs and brain. In subacute flow, edema is weak.

Fig. 176. Edema of the stomach wall of a piglet.

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  • The intestine is usually empty, the mucous membrane of it is pale pink, sometimes covered with mucus.
  • Mesenteric lymph nodes, regional stomach and small intestine, slightly enlarged, juicy on a cut.
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    1. Pronounced edema? swelling of the eyelids with infiltrationtheir loose fiber with watery liquid, in loose fiber ?? the walls of the stomach, intestine (thick), mesentery, lungs, as well as the abdominal cavity, less often in the forehead, the base of the auricles and the ventral wall of the stomach.

    Fig. 177. Swelling of the mesentery of the colon of a piglet.

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  • Stomach ?? serous or serousgastritis. Its wall is thickened to 1.5 נ cm, mainly in the cardiac region. On its incision, the gelatinous puffiness of the submucosal layer is clearly visible. The surface of the mucous membrane is folded, grayish-white in color, sometimes reddened, covered with mucus, a considerable quantity of dense, sometimes friable fodder masses.
  • Colon ?? the phenomenon of edematous nature.
  • Liver in a state of dystrophy and congestive hyperemia.
  • Mesenteric and portal (less often submandibular and zaglute) lymph nodes are enlarged, juicy on a cut, sometimes with the presence of a red "border" under the capsule.
  • Spleen macroscopically with no visible changes. Histologically: the pulp is loosened, swollen, cellular elements in the central zone of many follicles in a state of necrobiosis.
  • In heart ?? dilatation of the right heart cavities.
  • Lungs in a state of hyperemia and edema.
  • Kidneys? serous glomerulonephritis.
  • In the brain, hyperemia
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    In subacute flow, changes are similar to acute form, but edematous disease is less pronounced and is complicated by toxic hepatodystrophy.

    Diagnosis taking into account epizootic data, the clinic makes pathological changes and results of bacteriological examination.

    When differentiating, enterovirus gastroenteritis, paratyphoid, anaerobic dysentery and others are excluded.

    Control questions to the topic

    1. Etiopathogenesis of colienterotoxemia.
    2. Pathological changes in the hyperacute and acute course of colienterotoxemia.
    3. Diagnosis of colitisterotoxemia.
    1. Kokurichev P.I. Atlas of pathological anatomy with. ??. animals. ?? M. Kolos, 1973
    2. Pathological anatomy with. ??. animals / Ed. Shishkova V.P. ?? M. Kolos, 1980. P. 285.
    3. Shishkov V.P. Zharov A.V. Naletov N.A. Autopsy and pathoanatomical diagnosis of diseases with. ??. animals. ?? M. Kolos, 1982. P. 207.
    4. Infectious diseases of animals / Ed. Osidze DF ?? M. Kolos, 1987. P. 207.
    5. Zharov A.V. Pathological anatomy of animals. ?? Moscow, 1995.
    6. Salimov V.A. Workshop on the pathological anatomy of farm animals. ?? M. Kolos, 2003.