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Home ?? Diagnostics ?? Pallor, swelling, weak pulse, pressure drop and other symptoms of anaphylactic shock

Anaphylactic shock is a complex of differentallergic reactions of an immediate type reaching extreme severity. This syndrome occurs usually in the first minutes after the ingestion of the antigen, regardless of its chemical structure or dosage. The method of penetration of the antigen into the body does not affect the rate of development of anaphylactic shock, but largely determines the characteristics of its clinical picture. Thus, inhalation administration of the antigen primarily causes the rhino-conjunctival syndrome and bronchospasm, subcutaneous or intramuscular injection-local reaction, hives and angioedema, intravenous administration-pronounced angioedema (allergic dermatosis and local reaction may be absent).

The most constant sign of anaphylacticshock is acute vascular insufficiency with a sharp drop in blood pressure, paleness or flushing of the face, cyanosis and profuse sweat; the pulse is most often threadlike, palpable with difficulty, sometimes only on the carotid arteries. In a number of cases (especially with coronary heart disease) acute coronary insufficiency with a severe anginal infection, various heart rhythm disorders, and various ECG changes (from flattening of the T wave to violations typical of large-heart attack of myocardial infarction) is noted.

In addition, acute respiratoryinsufficiency due to bronchospasm or angioedema of the tongue and larynx. Obstruction of the respiratory tract leads to the onset of pulmonary hypertension, which is manifested by a clear accent of the 2nd tone on the pulmonary artery and signs of an overload of the right heart sections on the ECG.

The combination of pulmonary hypertension with a sharp increasecapillary permeability sometimes leads to massive pulmonary edema (bubbling breath, the release of a large amount of frothy pink sputum, variously moist wheezing all over the surface of the lungs).

Severe hypoxia and acute cardiovascularInsufficiency is usually accompanied by cerebral edema with meningeal syndrome, psychomotor agitation, turning into adynamia, loss of consciousness, involuntary bowel movement and urination. There are also various cerebral disorders (from transient disorientation in time and the surrounding environment due to brain anoxia and dynamic cerebral circulation disorders to extensive subarachnoid hemorrhage). Less common are fibrillar twitchings of individual muscle groups, as well as generalized or localized tonic or clonic convulsions.

"Pallor, swelling, weak pulse, pressure drop and other symptoms of anaphylactic shock" article from section Allergy