Edema non-allergic

Basic data
Female gender
Age: 34 years old
Krasnoyarsk city
Weight: 50
Height: 152
Profession: гл. accountant, now on maternity leave.
Pets: cat 14 years old

Complaints and symptoms of the disease
a. Your complaints:
rashes throughout the body, swelling on the face, mostly on the lips.
b. When did they first appear?
9 weeks ago
at. How often they appear (every day, every other day, 1 p / week, etc.):
everyday
At what time of the day (and season of the year) are the most pronounced?
night, day passes, also after a walk on the hands, feet, cheeks a little.
etc. What do you think provokes the appearance of symptoms (stress, drugs, food, etc.)?
food: sweet, baking, seemingly dairy.
e. If you have other complaints (for example, pain in muscles and joints, temperature, etc.)?
Periodic pressing pains in the right hypochondrium.

Treatment and Diagnosis
a. Did you go to the doctor (when)?
Yes, right away.
b. What was the treatment, what was the effect of the treatment?
Fenistil drops (on GV "nothing is impossible") 1 week - nothelped or assisted, then loratadin 1 * 2p 2 ned - it is better, then cetirizine about 1 month has reached 5 tabs + suprastin, now I do not feed the child: diazolinum 1 * 3p, atarax (it is necessary?) 1 for the night, ksizal 1p. in the evening. Ketotifen 1 at night 1.5 months, 1 week did not drink - worse, now 1 * 2p is better. Enterosgel 2 weeks, then polysorbate 1.5 months. now do not receive. Cholagogue: allochole 1month, then hofitol 2 weeks, then ursofalk - there were pains, deterioration, I do not accept. Plasmapheresis 4 r, improvement.

Have you had an allergic reaction before?
For food: no
medicines, vaccines: no
when cleaning (on dust): no
cosmetics: no
animals: no
pollen of plants: no
metal products and ornaments: no
latex: no
bites / stings by insects: no
others: no matter what ever

Were allergic reactions in your relatives? Papa once had hives in the armpits, small.

All the drugs you take now
Diazolin 1 * 3p (3 days), ketotifen 1 * 2 p. (all the time, first 1 * 1p), atarax - 1 at night (2 weeks), xizal - 1p in the evening (3 days). Fenistil gel - on the lips (swelling) and eyelids (urticaria if a lot, then the lips will sweat) every evening (so swells a little at all).

Hello! 9 weeks there is a urticaria. swelling of the face. I have a child 1 year, 0.5 months ago, completed breastfeeding. To an allergy I have no inclination. About 3 years, since late autumn, itch is closer to the evening, after the scratching, flesh-colored traces of urticaria appear, which passed independently after 20 minutes, especially did not bother, did not contact the doctor. Acute hives for the first time. After the first rashes (before the new year) there was a break for about 3 days, then the rashes repeated (after the new year) and did not pass, there were swelling of the face, mostly lips, once hoarseness. Edema was removed with prednisolone, dexamethasone, and I remove small ones with antihistamines. Droppers and IV injection of sodium thiosulfate, calcium chloride, calcium gluconate, the effect was not given. Sometimes the pressing pain behind in the right hypochondrium disturbs, first appeared a year ago on a long pregnancy, was examined, the cause was not found, the child decided to press on the diaphragm. On a diet, pain does not happen. Has addressed internally to the dermatologist-allergist, the allergist, the immunologist, the therapist, the gynecologist, the Internet consultation of the endocrinologist, has started to be surveyed under recommendations of the doctor with an accent on GASTROINTESTINAL TRACT and a parasite. From the found: c-reactive protein 10.8; The polyp in the gallbladder was first detected. I can not apply, but I gave the feces three times by the method of Kato - negative; biochemistry: ALT, ASAT, bilirubin, creatinine, cholesterol is normal; the general or common analysis of urine in norm or rate. Now I give stool by Parasep method three times, the first - negatively, before it I handed over once - negatively. Also has handed over a feces on PTSR antibodies to ljamblijam, it is yet ready. 4 plasmapheresis procedures were performed, the condition improved. I'm on a diet (beef, rice, buckwheat, vegetables, apples, pears). After 10 days, the doctor plans treatment with Ruzam, also said "I do not know if it makes sense to do injections of an autoserum after plasmapheresis." Tell me, is this the right direction? Do I need a follow-up? I was not given a reason, or rather said "this is not an allergy." Do I need treatment from a gastroenterologist (especially I have no complaints)? Does it make sense to take the immunogram, hemostasis, lipid profile of blood, blood proteins (I did not give it to plasmapheresis)? At the present time, a cycle has not yet been established, does this matter for urticaria (the gynecologist has said nothing yet)? I enclose the survey.

Quote: > After 10 days, the doctor plans treatment with Ruzam, also said "I do not know if it makes sense to inject the autoserum after plasmapheresis." Tell me, is this the right direction? Do I need a follow-up? I was not given a reason, or rather said "this is not an allergy." Do I need treatment from a gastroenterologist (especially I have no complaints)? Does it make sense to take the immunogram, hemostasis, lipid profile of blood, blood proteins (I did not give it to plasmapheresis)? At the present time, a cycle has not yet been established, does this matter for urticaria (the gynecologist has said nothing yet)? I enclose the survey.

1. Ruzam is not used in the world for the treatment of hives.
2. You can make an intradermal test with autologous serum + blood for antinuclear antibodies. Perhaps hives have an autoreactive / autoimmune basis. Especially considering that there is an autoimmune thyroiditis (increased AT to TG, TPO).


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Sincerely, Kolkhir Pavel Vladimirovich, Allergist-Immunologist, Ph.D.
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