Quincke edema to which doctor to contact
- What is angioedema angioedema
- What provokes Angioedema angioedema
- Symptoms of Quincke Angioedema
- Diagnosis of angioedema angioedema Quincke
- Treatment of angioedema angioedema Quincke
- Prevention of angioedema angioedema Quincke
- What doctors should be treated if you have angioedema Quincke
What is angioedema angioedema
Quincke Angioedema (oedema angioneuroticum Quincke) - a disease characterized by severely developing limited deep swelling of the skin and subcutaneous tissue or mucous membranes, sometimes spontaneously disappearing and often recurring.
It was first described by the German therapist Quincke (1862). At the heart of the development of angioedema angioedema Quincke is an allergic reaction of the immediate type. Under the influence of biologically active substances (histamine, serotonin, heparin, etc.), released during an allergic reaction in a previously sensitized organism, the permeability of microvessels increases and edema of the tissues develops. Quincke's edema is often combined with hives, as both of these diseases have a common pathogenesis.
What provokes Angioedema angioedema
The cause of Quincke's edema may be the effect ofvarious food, medicinal allergens (sulfonamides, antibiotics, acetylsalicylic acid, bromides, etc.), cosmetics, odors, increased sensitivity to cold. A number of authors in the pathogenesis of the edema of Quincke emphasize heredity, increased excitability of the autonomic nervous system, foci of chronic infection, diseases of the gastrointestinal tract.
Symptoms of Quincke Angioedema
The disease begins suddenly. Within a few minutes, sometimes more slowly, a pronounced limited edema develops in different parts of the body or mucous membrane of the mouth. The color of the skin or mucous membrane of the mouth does not change. In the area of the edema the tissue is strained, with pressure on it, the pits do not remain, palpation is painless. The most often the Quincke's edema is located on the lower lip, eyelids, tongue, cheeks, larynx. When swelling of the tongue, it significantly increases and hardly fits in the mouth. Developed edema of the tongue and larynx is most dangerous, since it can lead to the rapid development of asphyxia. The process in these areas is developing very quickly. The patient feels difficulty breathing, develop aphonia, cyanosis of the tongue. Lack of necessary care can lead to the death of the patient.
If the Quincke's swelling captures the brain and the meninges, then there are corresponding neurological disorders (epileptiform seizures, aphasia, hemiplegia, etc.).
Edema Quincke can last for several hours ordays, then disappears without a trace, but in the future can periodically recur. Edema is rarely accompanied by pain, patients often complain of a feeling of tension of the tissues.
Diagnosis of angioedema angioedema Quincke
Quincke edema in the region of the lips should be differentiated from:
- the Melkerson-Rosenthal syndrome;
- erysipelatous inflammation;
- lymphostasis and collateral edema with periostitis.
With the Melkerson-Rosenthal syndrome, along withthe edema of the lip, which has a chronic recurrent course and is not as pronounced as the Quincke's edema, simultaneously reveals the folding of the tongue and the inflammation (neuritis) of the facial nerve. In erysipelas, in contrast to Quincke's edema, there is hyperemia in the area of lesions in the form of flame tongues. Quincke's edema in the area of the tongue is differentiated from different types of macroglossia. The diagnosis is mainly based on the history and the characteristic acute manifestation of the edema of Quincke.
Treatment of angioedema angioedema Quincke
When treating Quincke's edema The main thing is immediate removal of contactwith an allergen (in cases where it is possible). Apply antihistamines (dimedrol, suprastin, tavegil, pifolen, klaritin, fenkarol, etc.) intramuscularly or in mild cases inward in tablets 2-3 times a day. Assign ascorutin, which reduces vascular permeability.
When swelling of the larynx is additionally intramuscular25 mg of prednisolone hemisuccinate are administered. According to the patient's testimony, he is hospitalized in the ENT department or under the supervision of a surgeon in connection with the possible need for tracheostomy.
In severe cases of Quincke's edema, when there is a decrease in blood pressure, 0.1-0.5 ml of 0.1% adrenaline solution is injected subcutaneously.
Forecast is favorable for the localization of edema on the outer parts of the body and is serious when there is edema of the larynx, brain and meninges.
Prevention of angioedema angioedema Quincke
Prevention of recurrence of edema Quincke is achieved by preventing contact with the allergen that caused it.
What doctors should be treated if you have angioedema Quincke
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