Allergic reactions swelling of the quinine anaphylactic shock


Types and clinical characteristics acute allergic reactions and anaphylactic shock


The greatest value of acute allergic reactions have allergic urticaria (occurs most often), angioedema and anaphylactic shock. Factors that caused an allergic reaction,can be food products, medicines, cosmetics, animal hair, pollen of plants and much more. Allergy can cause almost any substance! It is necessary to carefully collect the anamnesis, although in many cases it is not possible to establish an allergen.


Allergic urticaria manifested in the form of bright pink spottedrashes on the skin of various sizes, irregular shape, sometimes draining. Can be located on any part of the body. As a rule, itching is accompanied by strong itching, there are traces of scratching on the skin. Occurs after a few minutes or hours after contact with the allergen.


Edema Quincke - areas of dense pale edema, usually inplaces of confluence of hives. There may also develop edema of the respiratory tract, gastrointestinal tract and other internal organs (visceral edema). This causes the corresponding clinical manifestations - dyspnea, pain in the chest and abdomen, dizziness, headache, etc.


Anaphylactic shock develops as a result of a sharp increase in the capacity of the vascular bed and the loss of a large amount of plasma, which leads to a decrease in the mass of circulating blood, a drop in blood pressure, and a detailed picture of shock.

Dangerous for the patient's life condition is also the development of acute asphyxia as a result of spasm and edema of bronchial mucosa.


Therapy for hives:


• Pipolphen, Tavegil, Suprastinum or Dimedrolum in an amount of 1-2 ml with 10 ml of physiological solution intravenously;
• in case of extensive skin lesions, as well aswith edema Quincke: in addition, 30-60 mg of prednisolone intravenously. With anaphylactic shock begin with intravenous injection of 60-120 mg of prednisolone;
• Anaphylactic shock is alsoepinephrine 0.1% 0.5-1 ml in 10 ml of physiological solution intravenously, and then perform infusion therapy and other anti-shock measures (see the section "Shock");
• In case of allergy to an insect bite or injection of a medicine, place the injection with a mixture of 0.3-0.5 ml of a 0.1% solution of epinephrine with 5-10 ml of isotonic sodium chloride solution.


In the absence of necessary medicines (inhike, train, etc.) use additional methods - gastric lavage, cleansing enema, giving the patient 5-10 tab. activated carbon, a tablespoon of a 5-10% solution of calcium chloride (it is also possible its intravenous administration), 2-3 tablets. dimedrol, suprastin, etc., lubricate the skin abundantly (especially in places of contact with the allergen and in the area of ​​the edema) with an ointment containing prednisolone or hydrocortisone (sometimes in medicine kits in the form of eye ointments).
Patients with urticaria in case of effectiveness(disappearance of itching, blanching and reduction of the rash) can be left at home. They should be recommended to continue taking antihistamines 3 times a day and pass an active challenge to the local doctor. Patients with Quinck edema and respiratory disorders are subject to compulsory admission to the therapeutic department. Patients with anaphylactic shock are taken to the intensive care unit or transferred to the resuscitation team.