Life after swelling of the quincke

Quincke's edema (other common names for thissevere condition - giant urticaria or angioedema) is a relatively rare reaction of the body to contact with certain substances.

The disease develops suddenly and rapidly,characterized by pronounced edema of the subcutaneous tissue. This condition got its name by the name of a doctor from Germany, Henry Quinke, who studied and described in detail the symptoms of this unusual reaction of the body to contacts with certain substances.

This condition develops in people in anyage, but, more often, angio-edema is observed in young women. In men of any age and older people of both sexes, Quincke's edema occurs less frequently, but it is impossible to exclude the risk of his formation. In children, giant urticaria is not diagnosed infrequently, according to statistics, about 2% of children are susceptible to this condition. As a rule, Quincke's edema develops more often in patients who have other diseases caused by reactions of the body associated with allergies - bronchial asthma, atopic dermatitis, etc.

Allergy is a predetermining factor in the development of angioedema. In fact, an allergy is an increased sensitivity of the body to certain substances (allergens).

Among the allergens, often causing the body's reaction, include some food, dust mites, plant pollen, drugs and animal hair

Giant urticaria is an immediate form of an allergic reaction, that is, the symptoms of this condition appear just a few minutes after contact with the allergen.

The mechanism of angioectal development is as follows:

  • after getting into the body of the allergen, active production of histamine in large quantities begins;
  • releasing histamine provokes immediate swelling of the tissues with simultaneous blood thickening.

To the factors that can provoke the swelling of Quincke can be attributed:

  • helminthic invasions;
  • parasitic infections;
  • digestive disorders caused by diseases of the digestive tract, in particular hepatitis;
  • hormonal failures.

There are two types of giant hives - allergic and non-allergic.

In the first case, edema develops as a responsethe body's reaction to contact with the allergen. Most often, this type of angio edema is noted with food allergies. Non-allergic edema develops because of congenital (hereditary) sensitivity to certain substances. In this case, the disease often proceeds chronically with periodic relapses.

To the causes that directly cause angioedemae. usually include:

  • the use of certain types of food (products with cocoa, strawberries, citrus fruits, dairy products, nuts, etc.);
  • drugs (penicillin series, preparations containing iodine, aspirin, etc.);
  • pollen of flowering plants;
  • bites stinging and blood-sucking insects (bees, wasps, bedbugs, ants, etc.);
  • home dust.

In the formation of a non-allergic type edema, the initiators can be the same allergens, as well as various nonspecific factors:

  • physical impact (cold, light, etc.);
  • stress;
  • intoxication;
  • infection.

Sometimes it is not possible to determine the immediate causes that provoked Quincke's edema, in this case, we are talking about the idiopathic nature of development.

Giant urticaria is characterized by a rapid onset, the symptoms appear suddenly and rapidly progress, swelling develops literally in front of eyes.

Theoretically, Quincke's edema can appear on any part of the body where there is an advanced layer of subcutaneous tissue.

  • Defeat of the respiratory system (more often the larynx). This condition is characterized by the following symptoms: the appearance of hoarseness, a characteristic "barking" cough, difficulty breathing. The patient himself is in anxious condition, the face acquires a pale, slightly bluish tint, sometimes a loss of consciousness is observed. This kind of edema is most dangerous for children, as the laryngeal edema can provoke suffocation.
  • Swelling of the face. It can develop edema of individual parts of the face - cheeks, lips. When the eye is swollen, the patient can not open his eyes. How does a person who developed facial angioedema, you can see in the photos posted in this section.
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  • The defeat of the genitals. At the same time, symptoms that are characteristic of acute inflammation of the urinary bladder and urinary retention may be observed.
  • Lesion of the mucous membranes in the oral cavity. The tongue, lips, tonsils swell. It often develops in children, but it can also be noted in adults.
  • Cerebral edema. With this development of the disease in adults and children develop convulsive syndromes, neurological disorders. Children often have syncope, hallucinations.
  • Lesion of the digestive tract. In this case, patients have symptoms of "acute abdomen", acute pain, vomiting, diarrhea, etc.
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    In children, Quincke's edema, most often, develops onface, capturing such parts as the lips, tongue and throat. In the photo, placed in this section, you can see how the patient looks in this case. The edema persists for several hours (less than a day), then passes without a trace.

    The danger of the disease is that because of the edemathe respiratory function worsens. If the patient does not receive help, he may die from asphyxia. In addition, the edema located on the face, with progression can capture the meninges, which threatens serious complications.

    How to act with an angioedema?

    As you can see in the photos posted in this section,the symptoms of giant urticaria are very specific, so that even a layman can understand what is happening. Because Quincke's edema represents an immediate threat to the life of the patient, every person should know how to act in such a situation.

    First of all, you need to call an ambulance, evenIn the event that the edema is presently insignificant and the patient feels well. The matter is that the situation can worsen at any moment and the patient will need urgent help.

    Until the ambulance arrived:

    • it is necessary to limit contact with the substance that provoked the reaction (if known);
    • it is necessary to try to calm the patient, having seated him in a comfortable position;
    • give a pill (for young children, half the tablet is enough) antihistamine drug (Diazolin, Zodak, etc.);
    • give a drink to the patient, it is important that he takes more fluids, allergens will be excreted in the urine. If possible, it is necessary to drink alkaline mineral water;
    • can be applied to the place of edema cold (ice);
    • open the windows, loosen clothes on the chest, so that nothing prevents the patient from breathing freely.

    If the patient's condition is very difficult, then it is better not to try to help him on his own, as wrong actions can only hurt.

    Urgent therapy and subsequent treatment of a patient is a matter for specialists. As a rule, the following therapy scheme is used:

    • Adrenalin. With subcutaneous injection of adrenaline (concentration of the solution 0.1%), the threat of asphyxia is eliminated, the reduced pressure is increased.
    • Desensitizing agents. These drugs are necessary to reduce the susceptibility of the body to allergenic substances. To this end, use antihistamines.
    • Hormonal preparations. To remove the edema, injections of glucocorticosteroids are used.
    • Diuretics. For faster removal of allergens, diuretics are used.
    • Detoxification. To remove toxins, enterosorption and hemosorption are used.

    When swelling Quinck patients (especially children) is recommended to be hospitalized in the allergic department of the hospital.

    • toning and stimulation of the sympathetic department of the nervous system (for this use vitamin C, preparations containing calcium);
    • normalization of the level of histamine in the blood (antihistamines);
    • strengthening the walls of blood vessels, eliminating their increased permeability (prescribe vitamins, ascorutin);
    • therapy aimed at desensitization of the body (gamma globulins, corticosteroids, vitamins).

    In the hereditary nature of giant urticaria, patients are injected with fresh plasma, which contains inhibitors of proteases and C1-esterase.

    The course of giant urticaria, as a rule,benign, the disease has a favorable prognosis. The greatest danger is Quincke's edema, which gives frequent relapses and proceeds with lesions of the mucous larynx, bronchospasm, anaphylactic shock.

    The only option for effective prevention of the development of giant urticaria in children and adults is the exclusion of contact withallergen. In addition, it is recommended to follow a hypoallergenic diet, periodic intake of antihistamines prescribed by a doctor. Questions about the implementation of preventive vaccinations and the prescription of medicinal and vitamin preparations for children who have undergone the edema of Quincke should be decided by a specialist individually with a preliminary assessment of all existing risks.

    Patients who have undergone angioedema in severe form, are advised to constantly carry an individual syringe with an adrenaline solution for emergency treatment in case of relapse.