Swelling of the quincine doctor
Edema Quincke (by the name of the German doctor N.I. Quincke, synonyms: angioedema, giant urticaria) - an acute allergic disease characterized by the onset of massive skin edema, subcutaneous adipose tissue and mucous membranes. Most often, Quincke's edema develops on the face, neck and upper body, the back of the hands and feet. Less swelling of the Quincke can affect the membranes of the brain, joints, internal organs.
Who is sick with Quincke's swelling?
Eden Quincke can get sick of any person,however, the greatest risk of developing this disease is observed in people with allergies of various types. Young women and children suffer from Quincke's swelling more often than men and older people.
What are the causes of Edema Quincke?
There are two types of Quincke edema: allergic and pseudoallergic.
Allergic Edema Quincke, like othersallergic diseases, arises as a result of a strong allergic reaction of the body, which develops in response to the penetration into the body of a specific allergen. Quincke's allergic edema is often combined with food allergy, bronchial asthma, urticaria, and hay fever.
Pseudoallergic Quincke edema (i.e. not allergic) develops in people with congenital pathology of the complement system. The compliment system is a group of blood proteins involved in the development of primary immune and allergic reactions. In human blood, these proteins are in an inactive state and are activated only at the time and place of entry into the body of a foreign antigen. In patients with pseudoallergic edema Quincke, the compliment system can be activated spontaneously or in response to thermal or chemical stimuli (heat, cold), leading to the development of a massive allergic reaction.
What are the symptoms of Quincke's edema?
Typical symptoms of Quincke's edema are acutethe resulting swelling of the facial tissues, the back of the palms, the neck, the back of the feet. The skin is pale in the area of the edema. Quincke's edema, as a rule, is not accompanied by itching. The developed swelling disappears without a trace within a few hours or days.
The most dangerous form of Quincke's edema isswelling of the pharynx, larynx, trachea that is observed in every fourth patient with Quinck's edema. Such patients suddenly have anxiety, difficulty breathing, loss of consciousness is possible. Examination of the mucous throat in such patients reveals swelling of the soft palate and palatine arch, narrowing of the lumen of the pharynx. In case of spread of the edema to the larynx and trachea, the patient may die from suffocation.
In children, Quincke's edema is manifested more or less limited foci of edema of the skin and mucous membranes.