An Introduction to the Quincke's Edema

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Quincke's edema - reaction to the impact of various biological and chemical factors, often of an allergic nature.

Named after the German physician Heinrich Quincke, who first described it in 1882.

Manifestations of edema Quincke - an increase in the face or part or limb. The color of the skin does not change.

Treatment of edema Quincke includes, in addition to medicines, mandatory detection of allergen or other provoking factors and their elimination.

Angioedema is different from normalhives only the depth of the skin. Edema of considerable size often appears in places with loose fiber - on the lips, eyelids, cheeks, oral mucosa, genital organs. In typical cases, it disappears completely after a few hours (up to 2-3 days). Patients with moderate and severe reactions should be hospitalized.

A special form stands out: hereditary angioedema, associated with a deficiency of the C1 inhibitor of the complement system. Men are more often ill, the family anamnesis is characteristic, development of an edema is provoked by microtraumas and stress. Often develops a laryngeal edema. The disease is treated according to other principles than allergic edema. Before surgical interventions it is necessary to take preventive measures.

For treatment, antihistamines are used, including the 2nd and 3rd generation:

  • Desloratadine (trade names: Eridez, Eden, Erius, Lauratec);
  • Cetirizine (trade names: Cetrin, Alerza, Allertec, Zetrinal, Zincet, Zirtek, Zodak, Letizen, Parlazin, Cetirinax, Allercaps, Aleron);
  • Fexofenadine (trade names: Telfast, Fexophastus, Fexadine).

This abstract is based on an article from Russian Wikipedia. Synchronization completed on 12.07.11 13:54:15
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