Swelling of the quincke assays
In the case of acute edema Quincke, its cause can beTo reveal without carrying out of specific researches from the anamnesis. If there is a suggestion that the basis of the Quincke's edema is the true allergy (for food, medicines, etc.), you need to put skin tests with a prick test. A negative result in these cases allows to exclude the risk of anaphylaxis development on these allergens.
It is also necessary to determine the relationship between the edemaQuincke and the impact of physical factors. It is important to ask the patient about the diet. This will help to identify foods that contain salicylates (citrus fruits, tomatoes, berries, peppers, tea, honey, mint, etc.), preservatives, dyes, natural amines.
It is also important to find out if the patient has taken analgesics or vitamin supplements containing aspirin or dyes.
Examination of patients with chronic Quinck edema and urticaria should include:
- Determination of antithyroid and antinuclear autoantibodies;
- Determination of the level of the C3 and C4 complement components;
- Determination of cryoglobulins;
- Determination of cold agglutinins;
- General blood analysis;
- Analysis for ESR and C-reactive protein;
- Definition of the hepatitis B virus and the Epstein-Barr virus;
- Analysis of feces for helminths, detection of dysbiosis;
- Functional liver tests;
- Radiography of the chest;
- Analysis of urine.
It is necessary to carry out differential diagnosticsbetween Quincke's edema and myxedema, mediastinal compression syndrome, congenital elephantiasis (Meij's syndrome), dermatomyositis. It is mistaken for the edema of Quincke, as well, chronic diseases of the cardiovascular system and kidneys that occur with diffuse pastosis and edema.