Edema during hives treatment


Acute hives and Quincke's edema are diseases,mainly of allergic origin, have received their name not for nothing, its main manifestations on the skin, there are blisters with severe itching, and the development of limited edema of the skin, with the failure to provide timely assistance can lead to complications, and sometimes even death.

In this regard, urticaria edema Quinck Clinic diagnosis of treatment are of no small importance. In women, the disease occurs more often, which is associated with their endocrine system.

Urticaria and Quincke's edema are often met, according tostatistics, in the world every 5 people, at least once in a lifetime suffered one of these conditions. Quincke's edema and urticaria often combine, but can also proceed independently. Their occurrence is provoked by taking medications: antibiotics, renitek, enap, introduction of X-ray contrast preparations, sulfonamides, non-steroidal anti-inflammatory drugs; bites of insects; food products: seafood, peanuts, chocolate, flower pollen; the introduction of vaccines, blood transfusions or serums, etc. Also, it develops as a result of exposure to the body of physical factors: cold, pressure, vibration, sunlight, cold.

For acute urticaria characterized by a rapid development of symptoms, from 2-3 minutes to several hours, and the same rapid disappearance of symptoms after treatment.

Clinic and Diagnosis of Acute Urticaria and Quincke Edema

It is not difficult to diagnose acute urticaria,as a rule, patients clearly indicate the relationship between impairment and the appearance of blisters on the skin with the ingestion of an allergen into the body. There are no reliable methods for the diagnosis of urticaria and Quincke's edema, the only correct way is to cancel the drug or stop contact with the putative allergen.

Start urticaria acute, there are numerous blisters onany area of ​​the skin, strongly itch, have a bright pink color, the touch is dense, of varying sizes in diameter, from 2-3 cm to 10 cm, tend to merge. After the therapy they disappear without a trace, the attack lasts from several hours to several days. Simultaneously with the eruptions on the skin, blisters appear on the mucous membranes: the oral cavity, the perineum. Very rarely there are blisters inside which there is an admixture of blood, in this case after themselves they leave pigmentary spots. In addition, patients complain of severe headache, fever, weakness.

Limited edema of Quincke (synonyms - giant urticaria orangioedema), it is characterized by a sharp development of the edema of the skin or mucous membranes, subcutaneously fatty tissue of the face: lips, cheeks, eyelids. To the touch the edema is warm, dense, the color is white, less often pink. Complaints in the form of itching or burning, usually absent. There is a feeling of pressure behind the sternum and panic, the body temperature can rise. Sometimes it is combined with urticaria, in which case blisters appear and a clinic of acute urticaria joins. Quincke's edema is especially dangerous if there has been an edema of the mucous larynx, then it threatens such complication as choking. In the case where the edema is localized in the orbit, there may be an eyeball deflection, and a visual impairment.

There is, a separate form of Quincke's edema,hereditary, associated with congenital deficiency of C1 - inhibitor. For him, the laryngeal edema is most common. This disease often affects men, the provoking factor is stress, treatment on other principles.

Treatment of urticaria and edema Quincke

It should begin with an immediate cessationreceipt of the allergen in the body. If the disease manifested itself in severe form, hospitalization in the hospital is mandatory. Further measures are taken to relieve the symptoms of the disease and quickly eliminate the allergen from the body. To do this, enterosorbents are used: activated carbon, polyphepam, enteros-gel, smectite. If necessary, cleansing enemas if the allergen has got into the body through food products. Intravenous infusions are combined with the use of diuretics. Further to the treatment, antiallergic drugs administered intravenously or intramuscularly are added: suprastin, tavegil, sodium theosulfate, but their use is strictly limited due to numerous side effects: dry mouth, drowsiness, suppression of the nervous system. Preference is given to the use of second generation antihistamines: parasitic, claritin, kestin, etc., and especially third generation drugs: telphast or erius, their advantage is that they do not experience addiction and minimal side effects.

If the treatment is ineffective,add the introduction of hormones of general action: prednisolone, hydrocortisone, dexamethasone, short courses for 5-7 days. Longer-term treatment is not recommended, due to the risk of side effects and the high probability of relapse after drug withdrawal.

In the treatment of hereditary edema Quincke isessential differences, in the acute period introduce fresh frozen plasma, aminocaproic acid, dinazol, diuretics (lasix, furosemide), systemic hormones.

A person who has at least once undergone urticariaor Quincke's edema, no matter what degree of severity, everyone should know about their disease, carry the data in which the diagnosis and recommendations are indicated, and carry medicines for first aid. Avoid contact with the allergen caused, disease. In the case, once manifested drug allergy, in the form of edema Quincke or urticaria, for further treatment with other medications, individual tests for sensitivity are conducted, since the likelihood of cross-allergy is high.