Cerebral edema and brain causes

Pulmonary edema in newborns. Causes of pulmonary edema in newborn infants

Pulmonary edema often can be observed in newborns.
Serious and relatively frequent cause of pulmonary edema newborns are dysrhythmic development,developmental disorder and prenatal asphyxia, hypoxic brain injury with subsequent cerebral hemorrhage, or hypoxemia and metabolic inadequacy due to the obsolescence of the placenta and the failure of its oxidative activity in the transferred fetus, in infarcts of the placenta, in fetuses of mothers with sugar disease, or fetal asphyxia, or due to prematurely caused respiratory activity and violent aspiration of amniotic fluid with an admixture of meconium, devscamir epithelium of the skin, hair, etc., or childbirth caused by hypoxia or anoxia caused by absolute or relative overdose of narcotic or analgesic agents, etc. taken by the mother, or by aspiration of vaginal mucus followed by obturation of larger airways, or the time of delivery or as a consequence of postpartum hemorrhage in the brain, or intracranial hemorrhage in general, or for other reasons.

A similar cause of pulmonary edema in newborns there may be swelling of the brain (as, for example, contusion, traumatic and other origin). From this it follows that hypoxemia arises from the lack of oxygen flow into the blood through the umbilical vein, or due to a lack of placenta (prenatal hypoxemia), or through the lungs (postpartum hypoxemia). After reaching a certain degree and duration, hypoxemia disrupts ganglion cells, capillary walls, and cardiac muscle. This often leads to circulatory insufficiency and hyperemia of internal organs, mainly of the lungs.

Heart Activity at first accelerated, gradually, however, sheslows down, and the heart sounds weaken. After childbirth, breathing also increases, and then, as soon as intracranial pressure rises, it slows down. Permeability of capillaries increases.

Irritability of the respiratory center to a varying degree decreases. Seizures of cyanosis may occur. In the state of circulus vitiosus, the reverse effect on the brain on the one hand, and the subsequent restriction of respiratory function of the lungs on the other hand. Although hypoxemia also increases the permeability of capillaries, but as long as the blood circulation is satisfactory, the lymphatic system is able to remove the protein capillary effusion before the fluid could penetrate into the alveolar cavities.

In those cases where circulation unsatisfactory, lymphatic drainage action is also inadequate (Drinker 1933, 1945, Bean 1956), and the more so when respiratory activity is disrupted.