Symptoms of periventricular edema in a newborn

Clinic and signs of cerebrocardial syndrome in newborns.

Clinical picture of cerebrocardial syndrome neuronography.

• In cases where there is a phenomenonthe rigidity of the heart rhythm in the syndrome of CNS depression, non-irosonogram determined signs of periventricular cerebral edema and "depletion of vegetative maintenance" on the cardiointervalogram.

• In children with moderate clinical manifestationscerebrocardial syndrome in the first week of life on neirosonogram, increased echolocation of the cerebral parenchyma of one- or two-sided localization, signs of symmetrical or asymmetric hydrocephalus, periventricular hemorrhages of small sizes.

• With severe manifestations of cerebro-cardialsyndrome on neirosonogram, intense foci of increased echomolarity of one- or two-sided localization, swelling and swelling of the brain, periventricular leukomalacia and subependimal hemorrhages.

A significant contribution to development of cerebrocardial syndrome introduces dysfunction of the central nervous system, namely, its vegetativedepartment. A series of studies in this direction in newborn children with perinatal hypoxic-ischemic pathology of the central nervous system convincingly proves this. Most of these babies show a high stress index, an increase in the sympathetic and parasympathetic components of the vegetative maintenance, and in some children the depletion of adaptive mechanisms in the form of a low stress index is determined. Against the background of regression of neurological symptoms, the frequency of vegetative regulation decreases more than 3 times, the proportion of the vagotonic component is reduced by half, sympathicotonia predominates. Positive neurologic symptoms are accompanied by a significant decrease in the stress index, which is more pronounced at the end of the second week after treatment (Azhkamalov SI 1998).

Studying the vegetative status in preterm neonates with hypoxicthe CNS lesion revealed that in the acute period of the disease the most frequently recorded hypersympathicotonic initial vegetative tone. In the early recovery period in preterm infants with severe CNS lesions, the stress index increases 1.9 times in comparison with the acute period of the disease. In the early and late recovery periods, the asymptaticotonic type of vegetative reactivity is 15%. Insufficient vegetative maintenance of activity in premature newborns with severe CNS lesions is noted in 64% of cases in the acute period of the disease. In the early recovery period, inadequate vegetative maintenance is diagnosed in 44% of children. Excessive vegetative support of activity is revealed in 30.7% of premature infants.

Researchers come to the conclusion that in premature newborns with hypoxic CNS damage with increasingseverity of the CNS lesion, an increase in the hypersympaticotonic initial vegetative tone, insufficient vegetative maintenance of activity due to asthenic and astenosympathetic reaction and fatigue reaction of the recovery period. These changes reflect a significant dysfunction of supra-segmental cerebral structures (Zhelev VA, et al., 2004).

Features of the state of the autonomic nervous system and its regulatory effect on cardiovascularsystem in newborn children who underwent chronic intrauterine hypoxia, showed in their studies L.V. Kozlova, OA The Coroid (2000). It was noted that such children in the first day of life showed a decrease in activity of the sympathetic part of the autonomic nervous system with a simultaneous increase in parasympathetic influences. The application of the loading test increases the activity of the parasympathetic department. On the basis of the data given, a conclusion is drawn that the transferred chronic intrauterine hypoxia causes a change in the vegetative status with a predominance of the sympathetic activity of the autonomic nervous system in the early neonatal period. The predominance of hypersympathicotonic reactivity indicates the intensity of the adaptation mechanisms, and the presence of asymptoticotonic reactivity reflects a reduction in reserve capacities.