Amlodipine can cause swelling of the legs

Amlodipine is effective in arterialhypertension, chronic form of ischemic heart disease, stable angina, unstable angina. The drug is taken orally in the form of tablets, the daily dosage is determined depending on the disease of the patient and can, if necessary, reach 10 mg. Do not prescribe amlodipine to patients with arterial hypotension, cardiogenic shock.

Manufacturer. CJSC "Canonfarma Production", Russia

Farm. Group. Antagonists of calcium ions

Average price. 64.7 rubles.

Amlodipine is a medicinal product thatis an selective blocker of calcium channels of the second class. Has a prolonged antihypertensive effect, which is caused by a direct relaxing effect on the smooth muscles of blood vessels and myocardium. The drug slowly sucks in the digestive tract, the action occurs 2-4 hours after ingestion and lasts for 24 hours. The maximum concentration in blood plasma ...
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2. Indications for use:

The drug is prescribed for treatment of arterialhypertension, as well as diseases such as stable and unstable angina, vasospastic angina, ischemic heart disease (including chronic form). The drug is taken to reduce the risk of developing a fatal form of coronary heart disease, stroke, nonfatal form of myocardial infarction ...
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Usually the dosage of the drug during treatmentarterial hypertension (uncomplicated form) is 2.5 mg once a day. If arterial hypertension is complicated by ischemic heart disease, then the dosage is 5 mg once a day. It should be noted that the maximum daily dose of the drug is 10 mg ...
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Amlodipine may cause the following side effectseffects: chest pain, shortness of breath, heart rhythm disturbances, edema of the extremities, dizziness, increased nervousness, depressive state, sleep and wakefulness disorders, increased anxiety, nausea, vomiting, gastritis, abdominal pain, dry mouth ...
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The drug is contraindicated for use if availablethe patient has arterial hypotension, cardiogenic shock, hypersensitivity to the components of the drug, which has an individual character. Also, care should be taken for patients with impaired liver function, diabetes, chronic heart failure ...
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At the moment, there is no data onStudies on the effects of amlodipine on fetal development, as well as on women during pregnancy. Therefore, the drug should be administered under the strict supervision of the doctor in extreme cases, when the potential benefit to the mother exceeds the potential risk for the unborn child ...
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7. Interaction with other drugs:

The toxic effects of amlodipine maystrengthen with simultaneous admission with drugs that reduce the activity of liver enzymes. Pharmacological properties of the drug are reduced when combined with NSAIDs (non-steroidal anti-inflammatory drugs), preparations containing estrogen ...
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The use of elevated doses of amlodipine can lead to symptoms such as tachycardia, hypotension, increased enlargement ...
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The drug is available in the form of tablets, which are packed in blisters ...
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Amlodipine should be stored in a place protected from sunlight and moisture ...
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Amlodipine is a vasodilator ofgroups of calcium antagonists. It lowers the tone of the walls of the vessels, there the tension is weakened and the increased pressure drops. Also, the drug relaxes the load on the heart. When hypertension and angina pectoris should take 5 mg of the drug once a day, regardless of food. If necessary, the doctor can double the dosage. The course of treatment is about a week. Amlodipine also be part of a comprehensive treatment. To maintain normal pressure appoint 2.5 to 5 mg of the drug per day, and to prevent an attack of angina pectoris - 10 mg per day. The drug can be used in diabetes, bronchial asthma and gout, it is also compatible with many drugs (it is undesirable to combine with neuroleptics, calcium, lithium and antiviral agents).

Amlodipine: indications for use

This drug is used in the treatmentarterial hypertension, it can be combined with diuretics, adrenoblockers and ACE inhibitors. With amlodipine, the risk of restoring myocardial vessels and treating patients with coronary angina in ischemic heart disease is reduced. In chronic persistent angina, this drug is used as a first-line agent in the treatment of myocardial ischemia due to the narrowing or spasm of the coronary arteries or their organic obstruction. The drug can be used in the presence of vasoconstriction (narrowing the lumen of the coronary vessels) or vasospasm both in monotherapy and in complex treatment with other antianginal drugs.

Amlodipine does not act immediately. Only by the second week there is an increase in blood pressure, as the constant concentration of the drug in the blood is detected in a week. The drug significantly reduces the pressure and normalizes it in most patients (up to 90%). Especially it is necessary for patients with coronary heart disease and elderly people, since they are interested in the smoothness of the drug, the stability of blood pressure during the day. This medicine, in addition to reducing blood pressure, also improves heart function. Patients taking amlodipine reduce the risk of getting complications of hypertension, strokes, and death.

Drugs often seen with amlodipine:

  • Amoxiclav (Antibacterial drug, broad-spectrum penicillin antibiotic used to treat otitis media, pneumonia, chancroid);
  • Phenazepam (Possesses anticonvulsant, hypnotic action. Used for reactive psychoses, sleep disorders, as an anticonvulsant);
  • Duphaston (Active substance: dydrogesterone (close to natural progesterone) .It does not have estrogenic, androgenic, anabolic activity);
  • Alflutop (Has analgesic, anti-inflammatory effect.) Main indications: osteochondrosis, traumatic dysostosis, paradontopathy);
  • Diazolin (an antihistamine is widely used in the treatment of allergic diseases, as hives, eczema, allergic conjunctivitis, asthma).

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